Scientist I/II, Immunotherapy – 1011 – Cambridge, MA

Job Description

Location: Cambridge, MA

What if you could repair broken genes?  That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases.

We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before.

Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world?  If the answer is yes, then Editas Medicine is the place for you.

The immunogenetics team is seeking a highly motivated immunologist/molecular biologist with expertise in cellular immunology/synthetic immunology/immuno-metabolism. The successful candidate will help build a new class of immuno-oncology products and will test novel engineered effector cell modalities using in vitro and in vivo human tumor models. This is an excellent opportunity to be at the cutting edge of engineered cell medicines by combining the power of cell therapy for oncology and CRISPR-based gene editing.

Key Responsibilities:
•Work closely with members of Immunogenetics team to innovate novel synthetic approaches and identify genome editing targets to enhance effector cell function
•Work cross-functionally with Editas’ platform groups to optimize strategies for effector cell editing
•Execute experiments to characterize genetically modify human effector cells using in vitro functional assays, and help design in vivo tumor treatment models evaluating strategies to improve efficacy of cellular therapeutics
•Present data to project group and larger multidisciplinary teams
•Execute research timelines to meet program and corporate objectives

Minimum Qualifications:
•PhD in immunology, cancer biology, or related field
•One or more years post-doctoral research or equivalent industry experience
•Expertise in isolating and propagating human effector cells and flow cytometry
•Experience with immunological assays to assess effector cell function
•Demonstrated ability to work within a goal-oriented team and independently as necessary
•Excellent communication (both written and oral), time management, record keeping and data analysis skills

Preferred Qualifications:
•Expertise in innate immune cell biology and/or immuno-metabolism, familiarity with metabolic assays and in vitro tumor organoid models
•Familiarity with CRISPR-based gene editing and gene transfer platforms (viral and non-viral)
•Demonstrated knowledge of immunology and/or gene therapy/gene editing applications for cancer including publications in peer-reviewed journals

We are an equal opportunity employer offering a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the US.

Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.